Fomepizole, Infusion

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KEY POINTS

• This medicine is given by IV to treat poisoning caused by methanol or ethylene glycol.
• This medicine may cause unwanted side effects. Tell your healthcare provider if you have any side effects that are serious, continue, or get worse.
• Tell all healthcare providers who treat you about all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take.

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What are other names for this medicine?

Type of medicine: antidote

Generic and brand names: fomepizole, infusion; Antizol

What is this medicine used for?

This medicine is given by IV infusion (slow drip through a needle into a large vein) to treat poisoning caused by:

• Ethylene glycol (such as antifreeze)
• Methanol (such as window wiper fluid) poisoning

This medicine may be used to treat other conditions as determined by your healthcare provider.

What should my healthcare provider know before I take this medicine?

Before taking this medicine, the healthcare provider should know if you have ever had:

• An allergic reaction to any medicine
• Kidney or liver disease

Females of childbearing age: Talk with your healthcare provider if you are pregnant or plan to become pregnant. It is not known whether this medicine will harm an unborn baby. Do not breast-feed while taking this medicine without your healthcare provider's approval.

How do I use it?

The infusion is given by a healthcare provider.

What should I watch out for?

You will be carefully monitored while receiving this medicine.

If you need emergency care, surgery, lab tests, or dental work, tell the healthcare provider or dentist you have received this medicine.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.

Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help.): Allergic reaction (hives; itching; rash; trouble breathing; tightness in your chest; swelling of your lips, tongue, and throat).

Serious (Report these to your healthcare provider right away.): Severe vomiting, seizures, slow or fast heartbeat, uncontrolled eye movements or vision problems, trouble urinating, severe dizziness or fainting, unusual tiredness or weakness, unusual bruising or bleeding, fever or sore throat, severe pain or redness at injection site.

Other: Pain at the spot where injection is given, headache, nausea, vomiting, diarrhea, dizziness, drowsiness, bad taste in the mouth, mild rash, hiccups, change in sense of smell, stomach pain, back pain, ringing in your ears.

What products might interact with this medicine?

No significant drug interactions have been reported.

If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.

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This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.

Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicine in the trash.

Keep all medicines out of the reach of children.

Do not share medicines with other people.