Raxibacumab, Injection

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KEY POINTS

• This medicine is given by IV to treat inhaled anthrax or to prevent anthrax disease when there are no other treatment options.
• This medicine may cause unwanted side effects. Tell your healthcare provider if you have any side effects that are serious, continue, or get worse.
• Tell all healthcare providers who treat you about all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take.

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What are other names for this medicine?

Type of medicine: monoclonal antibody; anthrax treatment

Generic and brand names: raxibacumab, injection; ABthrax

What is this medicine used for?

This medicine is given by IV infusion (slow drip through a needle into a large vein) to treat inhaled anthrax. It is used along with antibiotics. This medicine may also be used to prevent anthrax disease when there are no other treatment options.

This medicine may be used to treat other conditions as determined by your healthcare provider.

What should my healthcare provider know before I take this medicine?

Before receiving this medicine, tell your healthcare provider if you have ever had an allergic reaction to any medicine.

Females of childbearing age: Tell your healthcare provider if you are pregnant or plan to become pregnant. Do not breast-feed while taking this medicine without your healthcare provider's approval.

How do I use it?

These infusions are given by your healthcare provider. You may also given diphenhydramine (Benadryl) by mouth or by IV infusion (through a needle into a vein) before you receive this medicine. You will be monitored closely while you are receiving this medicine.

What should I watch out for?

You may have soreness, irritation, or pain where the infusion is given. If pain continues for more than a couple of days or becomes severe, or you have other symptoms that concern you, call your healthcare provider.

If you need emergency care, surgery, lab tests, or dental work, tell the healthcare provider or dentist you have received this medicine.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.

Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help.): Allergic reaction (hives, itching, rash, tightness in your chest, swelling of your lips, tongue or throat, trouble breathing).

Serious (Report these to your healthcare provider right away.): Dizziness or fainting, increased or irregular heart rate.

Other: Drowsiness; pain in your arm or legs; mild rash; warmth, redness, swelling, soreness, or itching at the place the infusion was given.

What products might interact with this medicine?

No significant drug interactions have been reported.

If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.

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This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.

Keep all medicines out of the reach of children.