Regadenoson, Injection

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KEY POINTS

• This medicine is given by IV as part of a stress test to diagnose heart disease.
• This medicine may cause unwanted side effects. Tell your healthcare provider if you have any side effects that are serious, continue, or get worse.
• Tell all healthcare providers who treat you about all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take.

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What are other names for this medicine?

Type of medicine: diagnostic agent

Generic and brand names: regadenoson, injection; Lexiscan

What is this medicine used for?

This medicine is given by intravenous injection as part of a stress test to diagnose heart disease.

This medicine may be used to treat other conditions as determined by your healthcare provider.

What should my healthcare provider know before I take this medicine?

Before taking this medicine, tell your healthcare provider if you have ever had:

• An allergic reaction to any medicine
• Asthma or other breathing problems such as COPD
• Any other heart problems
• Low or high blood pressure
• Seizures

Females of childbearing age: Tell your healthcare provider if you are pregnant or plan to become pregnant. It is not known whether this medicine will harm an unborn baby. Do not breast-feed while taking this medicine without your healthcare provider's approval.

How do I use it?

Your healthcare provider will give you this medicine. You will be closely watched when you are given this medicine.

Do not eat or drink anything with caffeine in it (for example, tea, coffee, cola, and chocolate) or take any caffeine-that contain medicines for at least 12 hours before using this medicine. Talk with your healthcare provider about this.

What should I watch out for?

This medicine may make you dizzy or drowsy for several hours after you get the shot. Do not drive or operate machinery unless you are fully alert. Getting up slowly after sitting or lying down may help. This medicine may also cause shortness of breath, headache, and flushing. These are temporary side effects.

Adults over the age of 65 may be at greater risk for side effects. Talk with your healthcare provider about this.

If you need emergency care, surgery, lab tests, or dental work, tell the healthcare provider or dentist you have received this medicine.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.

Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help.): Allergic reaction (hives; itching; rash; trouble breathing; chest pain or tightness in your chest; swelling of your lips, tongue, and throat); sudden weakness, numbness, or tingling, especially on one side of your body; sudden or severe headache; sudden trouble with vision, speech, balance, or walking.

Serious (Report these to your healthcare provider right away.): Chest pain; fast, slow, or irregular heartbeat; severe dizziness or fainting; trouble breathing; seizures.

Other: Headache; nausea; dizziness; flushing; temporary shortness of breath; change in sense of taste; irritation at the site of the injection.

What products might interact with this medicine?

When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Talk to your healthcare provider if you are taking:

• Caffeine in food, drinks, or medicines
• Dipyridamole (Persantine) (You may need to stop this medicine at least 2 days before this test. Talk with your healthcare provider about this.)
• Medicines to treat breathing or lung problems such as aminophylline and theophylline

Do not drink alcohol while you are receiving this medicine.

If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.

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This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.

Keep all medicines out of the reach of children.