Reslizumab, Injection

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KEY POINTS

• This medicine is given by IV to prevent asthma attacks.
• This medicine may cause unwanted side effects. Tell your healthcare provider if you have any side effects that are serious, continue, or get worse.
• Tell all healthcare providers who treat you about all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take.

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What are other names for this medicine?

Type of medicine: monoclonal antibody; asthma treatment

Generic and brand names: reslizumab, injection; Cinqair

What is this medicine used for?

This medicine is given by IV infusion (slow drip through a needle into a large vein) to prevent asthma attacks. It does not stop attacks that have already started. Your healthcare provider will prescribe another medicine to be used during an attack.

This medicine may be used to treat other conditions as determined by your healthcare provider.

What should my healthcare provider know before I take this medicine?

Before taking this medicine, tell your healthcare provider if you have ever had:

• An allergic reaction to any medicine
• A worm infection
• Cancer

Talk with your healthcare provider if you use another medicine during asthma attacks, or any oral or inhaled corticosteroid medicine.

Females of childbearing age: Tell your healthcare provider if you are pregnant or plan to become pregnant. It is not known whether this medicine will harm an unborn baby. Do not breast-feed while taking this medicine without your healthcare provider's approval.

How do I use it?

These infusions are given by a healthcare provider once every 4 weeks. Keep all appointments.

Do not stop using this medicine or any other asthma medicine without your healthcare provider's approval. Do not reduce the dose of any other asthma medicines unless your healthcare provider tells you to do so.

What should I watch out for?

Contact your healthcare provider right away if your asthma or other breathing problem gets worse.

Rarely, this medicine causes a severe allergic reaction. If you develop tightness in your chest, trouble breathing, hives, itching over your upper body, or swelling of your lips, tongue, and throat, contact your healthcare provider or get emergency medical treatment immediately.

This medicine may increase your risk for certain cancers. Talk to your healthcare provider about this.

This medicine may increase the risk that you will get a parasite (worm) infection if you travel to places where those infections are common. Talk with your healthcare provider about this.

If you need emergency care, surgery, lab tests, or dental work, tell the healthcare provider or dentist you have received this medicine.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.

Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help.): Allergic reaction (hives; itching; rash; trouble breathing; tightness in your chest; swelling of your lips, tongue, and throat).

Other: Redness, bruising, warmth, burning, or tenderness at the spot where the infusion is given; muscle pain; headache; stuffy or runny nose; sore throat; cough; tiredness; dizziness.

What products might interact with this medicine?

No significant drug interactions have been reported.

If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.

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This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.

Keep all medicines out of the reach of children.

Do not share medicines with other people.