Ipratropium Bromide, Inhalation/Nasal

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KEY POINTS

• This medicine is inhaled through the mouth to treat asthma or COPD. The nasal spray form of this medicine is used to relieve a runny nose caused by colds or allergies. Use this medicine exactly as directed.
• Do not use this medicine for sudden breathing problems. Your healthcare provider can prescribe a short-acting inhaled medicine to use when you have a sudden breathing problem.
• If you get this medicine in your eyes it can cause eye pain, blurred vision, or worsening of narrow-angle glaucoma.
• This medicine may cause unwanted side effects. Tell your healthcare provider if you have any side effects that are serious, continue, or get worse.
• Tell all healthcare providers who treat you about all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take.

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What are other names for this medicine?

Type of medicine: bronchodilator; anticholinergic

Generic and brand names: ipratropium bromide, inhalation; ipratropium bromide, nasal; Atrovent HFA; Atrovent Nasal

What is this medicine used for?

This medicine comes in two forms: a medicine you inhale through your mouth and a nasal spray.

The inhaled form treats breathing problems caused by asthma or COPD. It is breathed into your lungs through your mouth.

The nasal spray (in a non-aerosol pump bottle) is used to relieve a runny nose caused by colds or allergies. It does not relieve nasal congestion, sneezing, or postnasal drip (dripping from the back of the nose directly into the throat).

This medicine may be used to treat other conditions as determined by your healthcare provider.

What should my healthcare provider know before I take this medicine?

Before taking this medicine, tell your healthcare provider if you have ever had:

• An allergic reaction to any medicine
• An enlarged prostate gland or trouble urinating
• Glaucoma
• Kidney or liver problems

Females of childbearing age: Tell your healthcare provider if you are pregnant or plan to become pregnant. Do not breast-feed while taking this medicine without your healthcare provider's approval.

How do I use it?

The inhaled form comes in the form of a solution to be used in a nebulizer (electric misting device) or in an aerosol inhaler. Both are for inhalation by mouth. The nasal spray is available in a non-aerosol pump bottle for spraying into the nostrils.

Check the label on the medicine for directions about your specific dose. Be sure you know when to take the medicine and how much medicine you should take. Carefully follow the instructions in the medicine package for using this medicine. If you are not sure how to use this medicine, ask your healthcare provider or pharmacist for help.

Check with your healthcare provider before using the inhaled form of this medicine in children under age 18.

Check with your healthcare provider before using the nasal spray form of this medicine in children under age 5. An adult should supervise the use of the nasal spray form of this medicine by a child.

Use this medicine exactly as your healthcare provider prescribes. Do not use more of it, use it more often, or use it for a longer period than prescribed. Do not stop using this medicine without your provider's approval.

If you are using other inhaled medicines, ask your healthcare provider or pharmacist which you should use first. Use the other inhaled medicines only as directed by your healthcare provider.

What if I miss a dose?

Use this medicine regularly as prescribed. If you miss a dose, use it as soon as you remember unless it is almost time for the next scheduled dose. In that case, skip the missed dose and use the next one as directed. Do not use double doses. If you are not sure of what to do if you miss a dose, or if you miss more than one dose, contact your healthcare provider.

What if I overdose?

An acute overdose of this medicine is not likely to cause life-threatening symptoms. If you think that you or anyone else may have taken too much of this medicine, call the poison control center at 800-222-1222.

What should I watch out for?

This medicine is not intended to treat sudden bronchospasm (severe gasping for breath). Your healthcare provider will prescribe a different medicine that you inhale through your mouth for fast relief.

If you need to use the medicine more often, or if your symptoms get worse, contact your healthcare provider.

Do not get this medicine in or near your eyes because it can cause temporary blurred vision, worsening of glaucoma, vision halos, or eye pain. If you get some medicine in your eyes, flush them with cool water and contact your healthcare provider.

This medicine may make you dizzy or cause blurred vision. Do not drive or operate machinery unless you are fully alert and can see clearly.

If you need emergency care, surgery, lab tests, or dental work, tell the healthcare provider or dentist you are using this medicine.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.

Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help.): Allergic reaction (hives; itching; rash; trouble breathing; tightness in your chest; swelling of your lips, tongue, and throat).

Serious (Report these to your healthcare provider right away.): Increased trouble breathing, irregular or fast heartbeat, chest pain, trouble urinating; eye pain; severe vision changes or problems; severe or continued nosebleeds or nasal dryness (nasal spray).

Other: Headache, nausea, vomiting, dizziness, dry mouth or throat, hoarseness, cough, temporary blurred vision, trouble sleeping, sore throat, runny or stuffy nose, mild nosebleeds (nasal spray).

What products might interact with this medicine?

When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Talk to your healthcare provider if you are taking:

• Anticholinergic medicines such as atropine/diphenoxylate (Lomotil), benztropine (Cogentin), dicyclomine (Bentyl), glycopyrrolate (Cuvposa, Robinul), hyoscyamine (HyoMax, Levbid, Levsin), methscopolamine (Pamine), propantheline, and trihexyphenidyl
• Antidepressants such as amitriptyline, amoxapine, clomipramine, desipramine (Norpramin), imipramine (Tofranil), and nortriptyline (Pamelor)
• Antihistamines such as brompheniramine, chlorpheniramine (Chlor-Trimeton), cyproheptadine, diphenhydramine (Benadryl), hydroxyzine (Vistaril), and meclizine (Dramamine)
• Antipsychotic medicines such as chlorpromazine, clozapine (Clozaril, FazaClo), fluphenazine, haloperidol (Haldol), loxapine, olanzapine (Zyprexa), perphenazine, pimozide (Orap), quetiapine (Seroquel), risperidone (Risperdal), and thioridazine
• Bladder control medicines such as darifenacin (Enablex), fesoterodine (Toviaz), mirabegron (Myrbetriq), oxybutynin (Ditropan XL, Oxytrol), solifenacin (VESIcare), tolterodine (Detrol), and trospium
• Cyclobenzaprine (Amrix)
• Doxepin (Silenor)
• Nausea medicines such as metoclopramide (Metozolv, Reglan), prochlorperazine (Compro) and promethazine
• Other medicines to treat breathing or lung problems such as aclidinium (Tudorza), glycopyrrolate (Seebri), tiotropium (Spiriva), and umeclidinium (Incruse Ellipta)

If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.

How should I store this medicine?

Store this medicine at room temperature. Keep the container tightly closed. Protect it from heat, high humidity, and bright light.

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This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.

Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicine in the trash.

Keep all medicines out of the reach of children.

Do not share medicines with other people.